In this study, the median CK5/6 score was 10 (9–12), median E-cadherin score 8 (6–11), median MDR-1 score 3 (1–6), median EGFR score 10 (8–12), and median CK19 score 9 (6–12) in the lymph node metastasis group. The gene discussed is CDH1; the disease is metastatic malignant neoplasm in the lymph nodes.