GEPIA database analysis results showed that the expression level of TSP2 in gastric adenocarcinoma (stomach adenocarcinoma; STAD) was significantly positively correlated with the expression of a series of mismatch repair genes, PMS2, MSH6, MSH2, and MLH1 (P < 0.05, Supplementary Fig. 3). The gene discussed is MSH2; the disease is gastric adenocarcinoma.