For this purpose, we carefully titered UBIAD1 and NQO1 knockdown in SkMel28 and A375 melanoma cell lines at suboptimal level (UBIAD1KD Low and NQO1KD Low) (Fig. S4F) to avoid complete cell death as for UBIAD1KD and NQO1KD (Fig. 2A–B and Fig.4F). Here, NQO1 is linked to melanoma.