F10 and COVID-19: A hypercoagulable state of patients with COVID-19 was manifested as the derangement in the level of zymogens, cofactors, and endogenous anticoagulants, such as increased levels of factor V (FV), factor VIII (FVIII), factor X (FX), fibrinogen (FI), protein C (PC) and decreased amount of antithrombin (AT) (see Table 1).