In addition, we also analyzed MUC4 expression in two datasets (GEO accession: GSE17536, p<0.01 and GSE17537, p<0.01) and observed that patients with high MUC4 expression showed a significant improvement in overall and disease-free survival (Figure 1B), suggesting a protective role of MUC4 in CRC. Here, MUC4 is linked to colorectal carcinoma.