Overall, 16 and 20 different pathways were enriched in the control and NSCLC groups, respectively, with metabolic pathways, ribosome, biosynthesis of secondary metabolites, and pyrimidine metabolism being the distinct metabolic processes identified in the lung cancer group, while two-component system, microbial metabolism in diverse environments, and ABC transporters were significantly present in the control group. Here, ABCG2 is linked to lung carcinoma.