Quantification of the different RC phenotypes at different time points postinfection confirmed the complete absence of RCs in UBM5 H5pm4251 infection and showed that the course of infection in WT H5pg4100- and UBM2 H5pm4250-infected cells resembled what has been previously reported, a temporal transition from diffuse DBP distribution within the nuclei to dot-like structures at 8 and 16 hpi, the presence of classical replication compartments at 24 hpi, and, eventually, “ringlike” structures, which are late, coalescing RCs (Fig. 4C). This evidence concerns the gene BAP1 and infection.