EGFR and lung cancer: At the end of the observation period, 7 patients died of lung cancer from distant organ metastasis (for example to the brain and bone), 1 patient was alive without cancer, another was alive with adrenal metastasis and was treated with chemotherapy and another was alive with cancer and was using EGFR–TKI for pleural dissemination for approximately 2 years with almost complete remission.