As shown in Figure 2c, Cor‐sugars showed significant cytoplasmic accumulation in A549 cells which has been confirmed to be expressing high levels of GLUT1 transporters that is upregulated by the Warburg effect mediated tumor glycolysis (Figure 2d).[21, 22] In addition to the A549 cancer cells, the GLUT1‐dependent intracellular accumulation was further investigated using GLUT1‐transfected human embryonic kidney (HEK) 293FT cells, and by performing a competitive uptake‐inhibition study of Cor‐gal and Cor‐man with a GLUT inhibitor. The gene discussed is SLC2A1; the disease is cancer.