COVID‐19 patients are predisposed to developing various fungal infections during the course and in later stages of this disease, especially severely ill cases, due to a decrease of CD4 + T cells and CD8 + T cells leading to immune suppression. So the main objective of this case report is to document cases of oral and maxillofacial pathologies which are associated with COVID‐19 infection. This evidence concerns the gene CD4 and fungal infectious disease.