Consistently, CD36 inhibition by genetic or pharmacologic means impairs tumor growth, cell migration, and metastasis formation in many of these cancers.2,6 CRC cells appear to rely on the FFA chaperones, FABP4 and FABP5, rather than CD36, for exogenous FFA uptake and lipid accumulation. The gene discussed is FABP4; the disease is colorectal carcinoma.