The [18F]AlF-NOTA-HER2 affibody showed a significantly higher concentration in HER2+ tumors than in HER2– tumors at each time point (p = 0.003, 0.016, and 0.010, respectively; Figure 4), which was consistent with the tumor/muscle ratio (T/M) (p = 0.046, 0.046, and 0.002, respectively). This evidence concerns the gene ERBB2 and neoplasm.