For example, RPL23A, RPL5, NPM1, TP53, CBX2, SURF6, MYC, PRMT1, POU5F1, SYN1, RARA, SQSTM1, CBX5, CBX1, LBR, IPO5, FMR1, TIA1, and SGOL1 were significantly upregulated in COAD samples (Figure 5A). The gene discussed is SQSTM1; the disease is colon adenocarcinoma.