For example, RPL23A, RPL5, NPM1, TP53, CBX2, SURF6, MYC, PRMT1, POU5F1, SYN1, RARA, SQSTM1, CBX5, CBX1, LBR, IPO5, FMR1, TIA1, and SGOL1 were significantly upregulated in COAD samples (Figure 5A). Here, POU5F1 is linked to colon adenocarcinoma.