For example, RPL23A, RPL5, NPM1, TP53, CBX2, SURF6, MYC, PRMT1, POU5F1, SYN1, RARA, SQSTM1, CBX5, CBX1, LBR, IPO5, FMR1, TIA1, and SGOL1 were significantly upregulated in COAD samples (Figure 5A). This evidence concerns the gene RARA and colon adenocarcinoma.