Svejgaard et al. (Svejgaard et al., 2015) demonstrated that both cytokines IL-6 and IL-8 improve 3D aggregation of the human thyroid cancer cell lines (ML-1 and RO-82-W-1) using the liquid overlay technique and that these cytokines induced the protein expression of β-actin, β1-integrin, talin-1, and Ki-67. The gene discussed is CXCL8; the disease is thyroid cancer.