Liang et al. reported that miR-34a was increased after DNMT1 downregulation, leading to suppression of stemness markers expression, including CD133, CD44, Oct4, Sox2, Bmi1 and ABCG2 in osteosarcoma stem-like cells (Liang et al., 2019b). The gene discussed is POU5F1; the disease is osteosarcoma.