CD8A and neoplasm: Immune-enrich-Stroma subtypes mainly enrich tumor immune-related molecular signatures, including T cell-inflamed GEP, Expanded immune signature, Immunophenoscore, Immune enrichment score, CD8 T cell exhaustion, myeloid-derived suppressor cells (MDSC), cytotoxic cells, Immune cell subset, etc. At the same time, it also enriches PD1 and stroma related signatures, including anti-PD-1 resistant, nivolumab responsive and normal stroma.