In addition, LOX-1 activated by ox-LDL reduces the expression of epithelial markers (E-cadherin and plakoglobin) and the expression of mesenchymal markers (vimentin, N-cadherin, snail, slug, etc), which lead to EMT that can further induce the invasion and migration of prostate cancer cells (20). The gene discussed is OLR1; the disease is prostate cancer.