- Transcriptional analysis of CT-26 KRAS G12C tumours after 2 days of sotorasib: significant increased of interferon signaling, CXCL10 and CXCL11 chemokines, MHC and TLR score, NK cell score, T-cell function and cytotoxic function score. The gene discussed is CXCL10; the disease is neoplasm.