To explore the possible mechanisms involved in LINC00689 and ELFN1-AS1 effects on UVM progression, we performed KEGG assays and found that LINC00689 could influence the survivals of UVM patients via herpes simplex virus 1 infection, Epstein-Barr virus infection, human T-cell leukemia virus 1 infection, and human papillomavirus infection. Here, ELFN1 is linked to human papilloma virus infection.