STAG3 and ovarian cancer: Microarray analysis associated STAG3 gene expression with tumorigenicity in ovarian cancer cell lines (Notaridou et al., 2011) while another study reported that multiple meiotic genes, including STAG3, are aberrantly activated during mitotic catastrophe in lymphoma cells after irradiation and may mediate chromosomal mis-segregation and genome reduction (Kalejs et al., 2006).