DMC1 and cancer: Interestingly, the upregulation of DMC1 was reported in a number of studies to drive the resistance of cancer cells to various cytotoxic and genotoxic agents (Kalejs et al., 2006; Erenpreisa et al., 2009; Ianzini et al., 2009; Rivera et al., 2015; Salmina et al., 2019).