In BLCA, the status of the genes PTEN (MUT = 12, WT = 398), ERBB2 (MUT = 39, WT = 371) and FGFR3 (MUT = 64, WT = 346) were all detected with high AUROCs of 0.773 (0.684–0.826, p = 0.008), 0.747 (0.64–0.837, p < 0.001) and 0.78 (0.72–0.822, p < 0.001), respectively. This evidence concerns the gene PTEN and bladder transitional cell carcinoma.