CF airway neutrophils, but not blood neutrophils, from CF patients exhibit increased expression of GLUT1, neutral amino acids transporter 2 (ASCT2) and inorganic phosphate transporter 1 & 2 (PiT1, PiT2) compared to normal neutrophils, suggesting that metabolic adaption processes occur in neutrophils upon their recruitment from blood into CF airway lumen (122). The gene discussed is SLC20A1; the disease is cystic fibrosis.