Besides, the expression of TYMP was correlated with the expressions of the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, PMS2, and EPCAM) and DNA methylation regulatory genes (DNMT1, DNMT2, DNMT3A, and DNMT3B) in various cancer types (Supplementary Figures S9E, F). This evidence concerns the gene MSH2 and cancer.