In contrast, interactions between PT150 and AR seem to associate more closely with genes associated with viral entry, such as Tmprss2, Ace2, Foxa1 and Fkbp5. These findings highlight the importance of these corticosteroid receptors for modulating both viral entry and immunologic response to infection with SARS-CoV-2 and utility of PT150 in modulating their activity. This evidence concerns the gene TMPRSS2 and infection.