After that, we further compared the ratios of CD8 TEM GZMK, CD8 TEM GNLY, and CD8 TEM TRAV27 to CD8 Naïve between patients with ASS-ILD and HDs, respectively; only the differences in the ratio of CD8 TEM GNLY to CD8 Naïve were statistically significant between patients and HDs (Figure 5C). This evidence concerns the gene CD8A and interstitial lung disease.