Finally, women of the PCOS/hPRL group had a trend for a less explosive response to the LHRH test (mean LH T30/LH T0 ratio = 6.4) as compared to women of the PCOS/nPRL group (mean LH T30/LH T0 ratio =13.31) however without reaching statistical significance (p=0.671). The gene discussed is PLOD1; the disease is polycystic ovary syndrome.