CDKN2B and type 2 diabetes mellitus: In addition to the SNP rs1412830 located at the CDKN2B-AS1 region, we observed four overlapping significant loci (index SNPs: rs12453682, rs1381274, rs2867112, and rs4790874) in the genome-wide cross-trait meta-analysis of smoking status–T2D and smoking status–CAD.