CDKN2B and type 2 diabetes mellitus: The most significant locus (index SNP rs1412830, pmeta = 3.03 × 10−34) was mapped to the CDKN2B-AS1 region, which was also found to be significant in the cross-trait meta-analysis for smoking status and T2D (pmeta = 2.63 × 10−17) or MI (pmeta = 1.45 × 10−23) (Figure 3).