In the <45 years subgroup, gender, tumor size, multifocality, bilateral tumor, degree of capsule invasion, Hashimoto’s thyroiditis and serum thyroglobulin had significant associations (P<0.05) with CLNM, and there were no significant associations of chief complaint duration, margin on ultrasonogram, calcification on ultrasonogram, tumor aspect ratio, TSH and nodular goiter with CLNM (P>0.05). This evidence concerns the gene TG and Hashimoto thyroiditis.