The results showed that large tumor size (P<0.05), extra-thyroid extension (P<0.05) and thyroglobulin level >40 ng/ml (OR=2.985, 95% CI 1.379-6.462; P<0.05) were independent risk factors for CLNM; meanwhile, Hashimoto’s thyroiditis (OR=0.532, 95% CI 0.324-0.874; P<0.05) were protective factors of CLNM. Here, TG is linked to neoplasm.