Data comparing the differences between controls and PCOS groups following exercise showed significant differences for C1q (P = 0.005), C3 (P = 0.036), C4 (P = 0.01), factor B (P = 0.004), factor H (P = 0.005), properdin (P = 0.005), and C4b (P = 0.009) (Table 1). This evidence concerns the gene C4B and polycystic ovary syndrome.