Among these genes were glucose-6-phosphate isomerase (GPI), respiratory chain complex NADH-coenzyme Q (CoQ) reductase, 7-dehydrocholesterol reductase, and thioredoxin 2, which were all related to adipocyte metabolism, further indicating that DMRT2 could be involved in adipocyte function and insulin resistance. This evidence concerns the gene DMRT2 and Insulin resistance.