Among these genes were glucose-6-phosphate isomerase (GPI), respiratory chain complex NADH-coenzyme Q (CoQ) reductase, 7-dehydrocholesterol reductase, and thioredoxin 2, which were all related to adipocyte metabolism, further indicating that DMRT2 could be involved in adipocyte function and insulin resistance. The gene discussed is GPI; the disease is Insulin resistance.