The mean age, number of smokers, drinkers, rates of diabetes mellitus, hypertension, coronary heart disease, COPD, levels of TGs, TC, HDL-C, LDL-C, CRP, fibrinogen, and levels of D-dimer were not significantly different between ESUS cases and LAA ischemic stroke cases (p > 0.05). This evidence concerns the gene CRP and coronary artery disorder.