While T1DM is characterized by hyperglycemia secondary to lack of endogenous insulin production, T2DM is associated with systemic insulin resistance and is associated with metabolic syndrome, a cluster of metabolic derangements including hypertension, increased central adiposity, and hypertriglyceridemia (Samson and Garber, 2014; Katsarou et al., 2017). Here, INS is linked to type 2 diabetes mellitus.