For example, the rise in vWF is likely to be greater following acute myocardial infarction than the rise observed in our study (Sakai et al., 2000), and it is unlikely that the magnitude of change in sP-selectin is equivalent to the 4-fold rise observed in disseminated intravascular coagulation (Chong et al., 1994). The gene discussed is VWF; the disease is acute myocardial infarction.