CD4 and Stroke: The seemingly contrasting finding from our study may be accounted for by the temporal sequence of T cell infiltration in ischemic stroke, whereby animal models of stroke have shown that the peak of T cell infiltration appears after 3–5 days in transient ischemia, while other report CD4 T cells showed a rise beginning from 7 to 30 days after stroke (Gelderblom et al., 2009; Shichita et al., 2009; Stubbe et al., 2012).