In particular, rs1800795 (IL6), rs62182086 (PNKD, PNKD Metallo-Beta-Lactamase Domain Containing), rs11218343 (SORL1), rs3745453 (ZSWIM4), rs1491942 (LRRK2, Leucine Rich Repeat Kinase 2) and female sex appeared as the most significant variables for predicting AD risk (Table 4). Here, LRRK2 is linked to Alzheimer disease.