When overexpression of a mutant transgene of α-synuclein (A53S) is combined in a mouse lacking endogenous tau, EEG-slowing induced by overexpression of α-synuclein is markedly attenuated, suggesting a clear link between these two proteins in seizure pathology witnessed in DLB (Peters et al., 2020). Here, SNCA is linked to Lewy body dementia.