This study also showed increased levels of SPM receptors, ALX and FPR2 (LXA4 and RvD1 receptors, respectively), and the EPA-derived RvE1 receptor, chemerin receptor 23 (ChemR23) on both glial cells, mainly astrocytes and neurons, in the hippocampus of AD brains as compared to control subjects. This evidence concerns the gene FPR2 and Alzheimer disease.