MBP and Peripheral demyelination: We and others recently demonstrated that metabolic oligodendrocyte stress, induced by intoxication with the mitochondrial toxin cuprizone, results in myelin basic protein (MBP) citrullination which triggers autoimmune inflammatory demyelination (Scheld et al., 2016; Caprariello et al., 2018; Kaddatz et al., 2021).