It has been recently described that a significant percentage of the proteins detected in tissue-purified Lewy bodies from DLB patients and cytoplasmic glial inclusions (CGI) of oligodendrocytes from multiple systemic atrophy (MSA) patients are synaptic vesicle proteins, including CD9 associated with exosomes (McCormack et al., 2019). Here, CD9 is linked to Lewy body dementia.