FMO5 and Mental deterioration: Drugs such as N-acetylcysteine, desferoxamine, and apocynin (inhibitor of NADPH-oxidase system) have already been tested and showed prevention of cognitive decline (Barichello et al., 2007; Reis et al., 2010; Hernandes et al., 2014), but so far, no clinical trials have been developed to test this possibility.