Yoshida et al. [18] reported a patient, had low-frequency SNHL and endolymphatic hydrops, carring SLC26A4 gene c.1105A > G mutation, In acute low-frequency SNHL, mild or more pronounced endolymphatic hydrops was reported in the cochlea in 88% of vestibula and 82% of ears [19]. This evidence concerns the gene SLC26A4 and sensorineural hearing loss disorder.