The pretreatment NLR was higher in SCLC and LCNEC (> 2.5: 63.51% vs. 64.71% vs. 18.18% vs. 27.78%, P = 0.001), but pretreatment PLR, LMR and CEA did not reveal significant differences in the intergroup comparison at baseline. The gene discussed is CEACAM5; the disease is small cell lung carcinoma.