To understand the crosstalk signaling axis between Met and EGFR family RTKs, we assembled a panel of MET-amplified cancer cell lines, derived from esophageal (OE33), gastric (KatoII, Okajima, Snu5, MKN45) and lung (EBC1, H1993) adenocarcinomas. This evidence concerns the gene MET and adenocarcinoma.