The stably overexpressed levels of DAB2IP measured by IHC staining in Kyse150 xenograft tumors are shown in Fig. 4B. Similar to the results observed in above in vitro experiment, the in vivo radiation-induced γH2AX foci assay indicated that, 24 h after receiving 6 Gy radiation, the unrepaired DNA damage was substantially increased in Kyse150-DAB2IP xenograft tumor tissues compared to parental control cell line xenograft tumors (Fig. 4C). This evidence concerns the gene DAB2IP and neoplasm.