Among 334 patients who had both urine LAM and urine X-pert testing, the number of TB cases detected using urine LAM [76 (22.8%)] was higher compared to the number of TB cases detected using urine X-pert [16 (4.8%)], proportion difference = 0.18; 95% CI: 0.13– 0.23 (p < 0.001) Of the 16 patients who tested positive using urine X-pert, 13 tested positive using urine LAM (LAM sensitivity = 81.3%; 95% CI: 54.4, 96.0%). The gene discussed is PSMB5; the disease is tuberculosis.