The mRNA expression of 12-LOX was negatively correlated with body fat % which is concordant with lower proportions of 14-HDHA in individuals living with obesity; however, greater expression of 5-LOX, COX-1 and CYP1B1 was observed in individuals living with obesity which was not concordant with the altered proportion of respective pathway oxylipins in these individuals. Here, CYP1B1 is linked to obesity disorder.