LRP1 and glioblastoma: Overexpressed low‐density lipoprotein receptor‐related protein‐1 (LRP‐1) is observed in both brain capillary endothelial cells and glioblastoma cells, which is a particularly appealing target.[67] Angiopep‐2 (ANG) peptide that derived from the Kunitz domain has a high affinity to LRP‐1.