Interestingly, we observed that pc and IS induced podosome-like structures and confirmed the podosome localization of WASP and WIP in blood mononuclear cells of control mice, which was not observed in cells from cKD-ILK animals, suggesting a putative role of ILK in podosome-mediated ex vivo adhesion of cells induced by pc and IS. This evidence concerns the gene WIPF1 and chronic kidney disease.