Remarkably, CFAP20 interacts with disease-causing proteins including: (i) ARL2BP, associated with RP, (ii) TBC1D32 and FOXJ1, related with ciliopathies, and (iii) LRRK2 and DICER1, involved in retinal degeneration in animal models. This evidence concerns the gene FOXJ1 and retinitis pigmentosa 1.