ZEB1 and colorectal carcinoma: Interestingly, hsa_circ_0001178 sponging miR-382, miR-587 and miR-616 to upregulate ZEB1, which in turn increase hsa_circ_0001178 expression via physically binding to hsa_circ_0001178 promoter region, thereby based on this positive feedback ceRNA axis, consequently facilitated the invasion and metastasis of CRC.244