One study showed that miR-103/107 potentiated the colonization of CRC cells at a metastatic site by targeting the known metastasis suppressors death-associated protein kinase (DAPK) and KLF4 in CRC cells.302 Similarly, in mice models of CRC, the overexpression of miR-103/107 enhanced local invasion and liver metastasis effects. Here, KLF4 is linked to colorectal carcinoma.